Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation

Mercedes Segovia, Sofia Russo, Mathias Jeldres, Yamil D Mahmoud, Valentina Perez, Maite Duhalde, Pierre Charnet, Matthieu Rousset, Sabina Victoria, Florencia Veigas 3, Cédric Louvet, Bernard Vanhove, R Andrés Floto, Ignacio Anegon, Maria Cristina Cuturi, M Romina Girotti, Gabriel A Rabinovich, Marcelo Hill

Cancer Cell. 2019 May 13;35(5):767-781.e6. doi: 10.1016/j.ccell.2019.04.003